San Francisco 49ers at Arizona Cardinals (November 16, 2025)

Game Recap

Week 11 of the 2025 season saw the San Francisco 49ers defeat the Arizona Cardinals 41-22.

Notes

• Score: San Francisco 49ersSFO defeat Arizona CardinalsARI 41-22
• Date: Sunday, November 16, 2025
• Game Time Kickoff: 4:05PM
• San Francisco 49ers Stats - Yards: 281, Turnovers: 0
• Arizona Cardinals Stats - Yards: 488, Turnovers: 3
• Game Odds:
• -- Line Point Spread: SFO by 3.5
• -- Over/Under: 48.5

Box Score

	1st	2nd	3rd	4th	TOT
SFO	13	12	10	6	41
ARI	7	3	0	12	22

Passing Leaders

PLAYER		C-A	YDS	TD	INT	LNG
Jacoby Brissett	ARI	47-57	452	2	2	34
Brock Purdy	SFO	19-26	200	3	0	30

Rushing Leaders

PLAYER		ATT	YDS	TD	LNG
Christian McCaffrey	SFO	13	81	2	20
Zonovan Knight	ARI	5	24	1	7
Brian Robinson Jr.	SFO	8	24	0	7
Emari Demercado	ARI	5	8	0	5
Michael Carter	ARI	2	6	0	3
Jacoby Brissett	ARI	2	-2	0	2
Mac Jones	SFO	3	-3	0	-1

Receiving Leaders

PLAYER		REC	YDS	TD	LNG
Michael Wilson	ARI	15	185	0	34
Trey McBride	ARI	10	115	1	28
George Kittle	SFO	6	67	2	30
Greg Dortch	ARI	6	66	1	17
Jauan Jennings	SFO	4	54	0	25
Christian McCaffrey	SFO	5	40	1	15
Kyle Juszczyk	SFO	2	26	0	21
Michael Carter	ARI	5	22	0	7

Team Total Rushing

TM	ATT	YDS	TD
ARI	14	36	1
SFO	25	95	2

Team Total Passing

TM	C-A	YDS	TD	INT	SCK
ARI	47-57	452	2	2	0
SFO	19-26	200	3	0	1

More Game Information On The San Francisco 49ers at Arizona Cardinals

• Attendance: 65,032
• Weather:
• Time of Game: 3:05 - 3 hours, 05 minutes