| PLAYER | # |
|---|---|
| Bijan Robinson (ATL) | 780 |
| Jahmyr Gibbs (DET) | 773 |
| Kenneth Walker III (KC) | 770 |
| Bucky Irving (TB) | 728 |
| James Cook (BUF) | 707 |
| Jaylen Warren (PIT) | 704 |
| Derrick Henry (BAL) | 632 |
| Jonathan Taylor (IND) | 610 |
| Tony Pollard (TEN) | 595 |
| Braelon Allen (NYJ) | 565 |
| Kyren Williams (LAR) | 548 |
| D'Andre Swift (CHI) | 545 |
| Chuba Hubbard (CAR) | 540 |
| Javonte Williams (DAL) | 528 |
| Bhayshul Tuten (JAX) | 492 |
| Aaron Jones (MIN) | 458 |
| Cam Skattebo (NYG) | 418 |
| Ollie Gordon II (MIA) | 408 |
| Emanuel Wilson (SEA) | 403 |
| Blake Corum (LAR) | 389 |
Note: Regular season only.