| PLAYER | # |
|---|---|
| Derrick Henry (BAL) | 159 |
| Jahmyr Gibbs (DET) | 158 |
| Bijan Robinson (ATL) | 150 |
| Jonathan Taylor (IND) | 148 |
| Bucky Irving (TB) | 147 |
| D'Andre Swift (CHI) | 143 |
| Kenneth Walker III (KC) | 141 |
| James Cook (BUF) | 138 |
| Javonte Williams (DAL) | 134 |
| Tony Pollard (TEN) | 133 |
| Jaylen Warren (PIT) | 119 |
| Chuba Hubbard (CAR) | 119 |
| Braelon Allen (NYJ) | 112 |
| Kyren Williams (LAR) | 112 |
| Emanuel Wilson (SEA) | 111 |
| Aaron Jones (MIN) | 110 |
| Bhayshul Tuten (JAX) | 110 |
| Ashton Jeanty (LV) | 108 |
| Quinshon Judkins (CLE) | 101 |
| Cam Skattebo (NYG) | 98 |
Note: Regular season only.