| PLAYER | # |
|---|---|
| Walter Payton (CHI) | 339 |
| Mark van Eeghen (LV) | 324 |
| Lydell Mitchell (IND) | 301 |
| Franco Harris (PIT) | 300 |
| Lawrence McCutcheon (LAR) | 294 |
| Chuck Foreman (MIN) | 270 |
| Sam Cunningham (NE) | 270 |
| Delvin Williams (SF) | 268 |
| Haskel Stanback (ATL) | 247 |
| Greg Pruitt (CLE) | 236 |
| Mike Thomas (WAS) | 228 |
| Tony Dorsett (DAL) | 208 |
| Chuck Muncie (NO) | 201 |
| Don Calhoun (NE) | 198 |
| Clarence Davis (LV) | 194 |
| Ronnie Coleman (TEN) | 185 |
| Robert Newhouse (DAL) | 180 |
| Wilbur Jackson (SF) | 179 |
| John Cappelletti (LAR) | 178 |
| Tony Galbreath (NO) | 168 |
Note: Regular season only.