2022 NFL Draft Round 5
| YEAR | RND | PICK # | TEAM | PLAYER | POS | COLLEGE |
| 2022 | 5 | 144 | WAS | Sam Howell | QB | North Carolina |
| 2022 | 5 | 145 | KAN | Darian Kinnard | T | Kentucky |
| 2022 | 5 | 146 | NYG | Micah McFadden | LB | Indiana |
| 2022 | 5 | 147 | NYG | D.J. Davidson | DT | Arizona St. |
| 2022 | 5 | 148 | BUF | Khalil Shakir | WR | Boise St. |
| 2022 | 5 | 149 | WAS | Cole Turner | TE | Nevada |
| 2022 | 5 | 150 | HOU | Thomas Booker | DE | Stanford |
| 2022 | 5 | 151 | ATL | Tyler Allgeier | RB | BYU |
| 2022 | 5 | 152 | DEN | Delarrin Turner-Yell | SAF | Oklahoma |
| 2022 | 5 | 153 | SEA | Tariq Woolen | CB | Texas-San Antonio |
| 2022 | 5 | 154 | JAX | Snoop Conner | RB | Mississippi |
| 2022 | 5 | 155 | DAL | Matt Waletzko | OL | North Dakota |
| 2022 | 5 | 156 | CLE | Jerome Ford | RB | Cincinnati |
| 2022 | 5 | 157 | TAM | Zyon McCollum | DB | Sam Houston St. |
| 2022 | 5 | 158 | SEA | Tyreke Smith | DE | Ohio St. |
| 2022 | 5 | 159 | IND | Eric Johnson | DT | Missouri State |
| 2022 | 5 | 160 | LAC | Otito Ogbonnia | DT | UCLA |
| 2022 | 5 | 161 | NOR | D'Marco Jackson | LB | Appalachian St. |
| 2022 | 5 | 162 | DEN | Montrell Washington | WR | Samford |
| 2022 | 5 | 163 | TEN | Kyle Philips | WR | UCLA |
| 2022 | 5 | 164 | LAR | Kyren Williams | RB | Notre Dame |
| 2022 | 5 | 165 | MIN | Esezi Otomewo | DT | Minnesota |
| 2022 | 5 | 166 | CIN | Tycen Anderson | SAF | Toledo |
| 2022 | 5 | 167 | DAL | DaRon Bland | DB | Fresno St. |
| 2022 | 5 | 168 | CHI | Braxton Jones | OL | Southern Utah |
| 2022 | 5 | 169 | MIN | Ty Chandler | RB | North Carolina |
| 2022 | 5 | 170 | HOU | Teagan Quitoriano | TE | Oregon St. |
| 2022 | 5 | 171 | DEN | Luke Wattenberg | OL | Washington |
| 2022 | 5 | 172 | SFO | Samuel Womack | CB | Toledo |
| 2022 | 5 | 173 | NYG | Marcus McKethan | OL | North Carolina |
| 2022 | 5 | 174 | CHI | Dominique Robinson | DE | Miami (OH) |
| 2022 | 5 | 175 | LVR | Matthew Butler | DT | Tennessee |
| 2022 | 5 | 176 | DAL | Damone Clark | LB | LSU |
| 2022 | 5 | 177 | DET | James Mitchell | TE | Virginia Tech |
| 2022 | 5 | 178 | DAL | John Ridgeway | DT | Arkansas |
| 2022 | 5 | 179 | GNB | Kingsley Enagbare | DE | South Carolina |
