2000 NFL Draft Round 4
| YEAR | RND | PICK # | TEAM | PLAYER | POS | COLLEGE |
| 2000 | 4 | 95 | CLE | Lewis Sanders | DB | Maryland |
| 2000 | 4 | 96 | NOR | Terrelle Smith | FB | Arizona St. |
| 2000 | 4 | 97 | CIN | Curtis Keaton | RB | James Madison |
| 2000 | 4 | 98 | GNB | Na'il Diggs | LB | Ohio St. |
| 2000 | 4 | 99 | PHI | Gari Scott | WR | Michigan St. |
| 2000 | 4 | 100 | ATL | Michael Thompson | T | Tennessee St. |
| 2000 | 4 | 101 | DEN | Jerry Johnson | DT | Florida St. |
| 2000 | 4 | 102 | ARI | David Barrett | DB | Arkansas |
| 2000 | 4 | 103 | PIT | Danny Farmer | WR | UCLA |
| 2000 | 4 | 104 | RAM | Kaulana Noa | T | Hawaii |
| 2000 | 4 | 105 | NYG | Brandon Short | LB | Penn St. |
| 2000 | 4 | 106 | MIN | Antonio Wilson | LB | Texas A&M-Commerce |
| 2000 | 4 | 107 | LAS | Junior Ioane | DT | Arizona St. |
| 2000 | 4 | 108 | SFO | John Keith | DB | Furman |
| 2000 | 4 | 109 | DAL | Kareem Larrimore | DB | West Texas A&M |
| 2000 | 4 | 110 | CLE | Aaron Shea | TE | Michigan |
| 2000 | 4 | 111 | LAC | Trevor Gaylor | WR | Miami (OH) |
| 2000 | 4 | 112 | DEN | Cooper Carlisle | G | Florida |
| 2000 | 4 | 113 | LAC | Leonardo Carson | DT | Auburn |
| 2000 | 4 | 114 | GNB | Anthony Lucas | WR | Arkansas |
| 2000 | 4 | 115 | KAN | Frank Moreau | RB | Louisville |
| 2000 | 4 | 116 | SEA | Marcus Bell | LB | Arizona |
| 2000 | 4 | 117 | MIA | Deon Dyer | FB | North Carolina |
| 2000 | 4 | 118 | MIN | Tyrone Carter | DB | Minnesota |
| 2000 | 4 | 119 | SEA | Isaiah Kacyvenski | LB | Harvard |
| 2000 | 4 | 120 | CAR | Alvin McKinley | DE | Mississippi St. |
| 2000 | 4 | 121 | BUF | Avion Black | WR | Tennessee St. |
| 2000 | 4 | 122 | IND | Josh Williams | DT | Michigan |
| 2000 | 4 | 123 | JAX | Joey Chustz | T | Louisiana Tech |
| 2000 | 4 | 124 | TEN | Bobby Myers | DB | Wisconsin |
| 2000 | 4 | 125 | CHI | Reggie Austin | DB | Wake Forest |
| 2000 | 4 | 126 | GNB | Gary Berry | DB | Ohio St. |
| 2000 | 4 | 127 | NWE | Greg Randall | T | Michigan St. |
| 2000 | 4 | 128 | TEN | Peter Sirmon | LB | Oregon |
| 2000 | 4 | 129 | WAS | Michael Moore | G | Troy |
