| PLAYER | # |
|---|---|
| Josh Jacobs (LV) | 1,653 |
| Derrick Henry (TEN) | 1,538 |
| Nick Chubb (CLE) | 1,525 |
| Saquon Barkley (NYG) | 1,312 |
| Miles Sanders (PHI) | 1,269 |
| Dalvin Cook (MIN) | 1,173 |
| Justin Fields (CHI) | 1,143 |
| Christian McCaffrey (SF) | 1,139 |
| Travis Etienne (JAX) | 1,125 |
| Aaron Jones (GB) | 1,121 |
| Jamaal Williams (DET) | 1,066 |
| Kenneth Walker III (SEA) | 1,050 |
| Rhamondre Stevenson (NE) | 1,040 |
| Najee Harris (PIT) | 1,038 |
| Tyler Allgeier (ATL) | 1,035 |
| Tony Pollard (DAL) | 1,007 |
| Dameon Pierce (HOU) | 939 |
| Austin Ekeler (LAC) | 915 |
| D'Onta Foreman (CAR) | 914 |
| Alvin Kamara (NO) | 897 |
Note: Regular season only.