| PLAYER | # |
|---|---|
| LaDainian Tomlinson (LAC) | 1,815 |
| Larry Johnson (KC) | 1,789 |
| Frank Gore (SF) | 1,695 |
| Tiki Barber (NYG) | 1,662 |
| Steven Jackson (LAR) | 1,528 |
| Willie Parker (PIT) | 1,494 |
| Rudi Johnson (CIN) | 1,309 |
| Brian Westbrook (PHI) | 1,217 |
| Chester Taylor (MIN) | 1,216 |
| Travis Henry (TEN) | 1,211 |
| Thomas Jones (CHI) | 1,210 |
| Edgerrin James (ARI) | 1,159 |
| Ladell Betts (WAS) | 1,154 |
| Fred Taylor (JAX) | 1,146 |
| Warrick Dunn (ATL) | 1,140 |
| Jamal Lewis (BAL) | 1,132 |
| Julius Jones (DAL) | 1,084 |
| Joseph Addai (IND) | 1,081 |
| Ahman Green (GB) | 1,059 |
| Deuce McAllister (NO) | 1,057 |
Note: Regular season only.