| PLAYER | # |
|---|---|
| Emmitt Smith (DAL) | 1,563 |
| Barry Sanders (DET) | 1,548 |
| Thurman Thomas (BUF) | 1,407 |
| Rodney Hampton (NYG) | 1,059 |
| Earnest Byner (WAS) | 1,048 |
| Gaston Green (DEN) | 1,037 |
| Christian Okoye (KC) | 1,031 |
| Leonard Russell (NE) | 959 |
| Mark Higgs (MIA) | 905 |
| Marion Butts (LAC) | 834 |
| Herschel Walker (MIN) | 825 |
| Rod Bernstine (LAC) | 766 |
| Reggie Cobb (TB) | 752 |
| Neal Anderson (CHI) | 747 |
| John Williams (SEA) | 741 |
| Harold Green (CIN) | 731 |
| Blair Thomas (NYJ) | 728 |
| Kevin Mack (CLE) | 726 |
| Allen Pinkett (TEN) | 720 |
| Robert Delpino (LAR) | 688 |
Note: Regular season only.