| PLAYER | # |
|---|---|
| Christian Okoye (KC) | 1,480 |
| Barry Sanders (DET) | 1,470 |
| Eric Dickerson (IND) | 1,311 |
| Neal Anderson (CHI) | 1,275 |
| Dalton Hilliard (NO) | 1,262 |
| Thurman Thomas (BUF) | 1,244 |
| James Brooks (CIN) | 1,239 |
| Bobby Humphrey (DEN) | 1,151 |
| Greg Bell (LAR) | 1,137 |
| Roger Craig (SF) | 1,054 |
| Ottis Anderson (NYG) | 1,023 |
| Bo Jackson (LV) | 950 |
| Herschel Walker (DAL) | 915 |
| Gerald Riggs (WAS) | 834 |
| John Stephens (NE) | 833 |
| Brent Fullwood (GB) | 821 |
| Tim Worley (PIT) | 770 |
| Johnny Hector (NYJ) | 702 |
| John Settle (ATL) | 689 |
| Marion Butts (LAC) | 683 |
Note: Regular season only.