| PLAYER | # |
|---|---|
| Freeman McNeil (NYJ) | 786 |
| Tony Dorsett (DAL) | 745 |
| Andra Franklin (MIA) | 701 |
| Marcus Allen (LV) | 697 |
| Billy Sims (DET) | 639 |
| Joe Cribbs (BUF) | 633 |
| Tony Collins (NE) | 632 |
| Pete Johnson (CIN) | 622 |
| Franco Harris (PIT) | 604 |
| Walter Payton (CHI) | 596 |
| Ottis Anderson (ARI) | 587 |
| William Andrews (ATL) | 573 |
| Chuck Muncie (LAC) | 569 |
| Wendell Tyler (LAR) | 564 |
| John Riggins (WAS) | 553 |
| Earl Campbell (TEN) | 538 |
| George Rogers (NO) | 535 |
| Mike Pruitt (CLE) | 516 |
| Wilbert Montgomery (PHI) | 515 |
| Ted Brown (MIN) | 515 |
Note: Regular season only.