| PLAYER | # |
|---|---|
| O.J. Simpson (BUF) | 2,003 |
| John Brockington (GB) | 1,144 |
| Calvin Hill (DAL) | 1,142 |
| Lawrence McCutcheon (LAR) | 1,097 |
| Larry Csonka (MIA) | 1,003 |
| Essex Johnson (CIN) | 997 |
| Dave Hampton (ATL) | 997 |
| Boobie Clark (CIN) | 988 |
| Floyd Little (DEN) | 979 |
| Tom Sullivan (PHI) | 968 |
| Lydell Mitchell (IND) | 963 |
| Mercury Morris (MIA) | 954 |
| Marv Hubbard (LV) | 903 |
| Ron Johnson (NYG) | 902 |
| Larry Brown (WAS) | 860 |
| Jim Bertelsen (LAR) | 854 |
| Emerson Boozer (NYJ) | 831 |
| Chuck Foreman (MIN) | 801 |
| Ed Podolak (KC) | 721 |
| Altie Taylor (DET) | 719 |
Note: Regular season only.