| PLAYER | # |
|---|---|
| Derrick Henry (TEN) | 280 |
| Rachaad White (TB) | 272 |
| Christian McCaffrey (SF) | 272 |
| Travis Etienne (JAX) | 267 |
| Joe Mixon (CIN) | 257 |
| Najee Harris (PIT) | 255 |
| Tony Pollard (DAL) | 252 |
| Saquon Barkley (NYG) | 247 |
| Chuba Hubbard (CAR) | 238 |
| James Cook (BUF) | 237 |
| Josh Jacobs (LV) | 233 |
| D'Andre Swift (PHI) | 229 |
| Kyren Williams (LAR) | 228 |
| Breece Hall (NYJ) | 223 |
| Kenneth Walker III (SEA) | 219 |
| David Montgomery (DET) | 219 |
| Javonte Williams (DEN) | 217 |
| Devin Singletary (HOU) | 216 |
| Bijan Robinson (ATL) | 214 |
| Raheem Mostert (MIA) | 209 |
Note: Regular season only.