| PLAYER | # |
|---|---|
| Ezekiel Elliott (DAL) | 304 |
| Saquon Barkley (NYG) | 261 |
| David Johnson (ARI) | 258 |
| Todd Gurley (LAR) | 256 |
| Adrian Peterson (WAS) | 251 |
| Jordan Howard (CHI) | 250 |
| Chris Carson (SEA) | 247 |
| Joe Mixon (CIN) | 237 |
| Peyton Barber (TB) | 234 |
| Christian McCaffrey (CAR) | 219 |
| Derrick Henry (TEN) | 215 |
| James Conner (PIT) | 215 |
| Lamar Miller (HOU) | 210 |
| Sony Michel (NE) | 209 |
| Marlon Mack (IND) | 195 |
| Alvin Kamara (NO) | 194 |
| Phillip Lindsay (DEN) | 192 |
| Nick Chubb (CLE) | 192 |
| Kareem Hunt (KC) | 181 |
| Melvin Gordon (LAC) | 175 |
Note: Regular season only.