| PLAYER | # |
|---|---|
| Arian Foster (HOU) | 351 |
| Adrian Peterson (MIN) | 348 |
| Alfred Morris (WAS) | 335 |
| Doug Martin (TB) | 319 |
| Marshawn Lynch (SEA) | 315 |
| Stevan Ridley (NE) | 290 |
| Jamaal Charles (KC) | 285 |
| BenJarvus Green-Ellis (CIN) | 278 |
| Shonn Greene (NYJ) | 276 |
| Chris Johnson (TEN) | 276 |
| Trent Richardson (CLE) | 267 |
| Steven Jackson (LAR) | 258 |
| Frank Gore (SF) | 258 |
| Ray Rice (BAL) | 257 |
| Matt Forte (CHI) | 248 |
| Reggie Bush (MIA) | 227 |
| Michael Turner (ATL) | 222 |
| Ahmad Bradshaw (NYG) | 221 |
| Darren McFadden (LV) | 216 |
| Mikel Leshoure (DET) | 215 |
Note: Regular season only.