| PLAYER | # |
|---|---|
| Earnest Byner (WAS) | 297 |
| Bobby Humphrey (DEN) | 288 |
| Thurman Thomas (BUF) | 271 |
| Marion Butts (LAC) | 265 |
| Neal Anderson (CHI) | 260 |
| Barry Sanders (DET) | 255 |
| Christian Okoye (KC) | 245 |
| Emmitt Smith (DAL) | 241 |
| Johnny Johnson (ARI) | 234 |
| Sammie Smith (MIA) | 226 |
| Ottis Anderson (NYG) | 225 |
| Derrick Fenner (SEA) | 215 |
| John Stephens (NE) | 212 |
| Cleveland Gary (LAR) | 204 |
| Barry Word (KC) | 204 |
| Merril Hoge (PIT) | 203 |
| James Brooks (CIN) | 195 |
| John Williams (SEA) | 187 |
| Herschel Walker (MIN) | 184 |
| Marcus Allen (LV) | 179 |
Note: Regular season only.