| PLAYER | # |
|---|---|
| Eric Dickerson (IND) | 388 |
| Herschel Walker (DAL) | 361 |
| Roger Craig (SF) | 310 |
| Joe Morris (NYG) | 307 |
| John Stephens (NE) | 297 |
| Greg Bell (LAR) | 288 |
| Curt Warner (SEA) | 266 |
| Mike Rozier (TEN) | 251 |
| Neal Anderson (CHI) | 249 |
| John Settle (ATL) | 232 |
| Gary Anderson (LAC) | 225 |
| Marcus Allen (LV) | 223 |
| Freeman McNeil (NYJ) | 219 |
| Thurman Thomas (BUF) | 207 |
| Dalton Hilliard (NO) | 204 |
| Ickey Woods (CIN) | 203 |
| Earl Ferrell (ARI) | 202 |
| John Williams (SEA) | 189 |
| Garry James (DET) | 182 |
| James Brooks (CIN) | 182 |
Note: Regular season only.