| PLAYER | # |
|---|---|
| James Wilder (TB) | 407 |
| Walter Payton (CHI) | 381 |
| Eric Dickerson (LAR) | 379 |
| Gerald Riggs (ATL) | 353 |
| John Riggins (WAS) | 327 |
| Tony Dorsett (DAL) | 302 |
| Earnest Jackson (LAC) | 296 |
| Sammy Winder (DEN) | 296 |
| Ottis Anderson (ARI) | 289 |
| Marcus Allen (LV) | 275 |
| Greg Bell (BUF) | 262 |
| Rob Carpenter (NYG) | 250 |
| Wendell Tyler (SF) | 246 |
| George Rogers (NO) | 239 |
| Freeman McNeil (NYJ) | 229 |
| Frank Pollard (PIT) | 213 |
| Boyce Green (CLE) | 202 |
| Alfred Anderson (MIN) | 201 |
| Wilbert Montgomery (PHI) | 201 |
| Larry Moriarty (TEN) | 189 |
Note: Regular season only.