| PLAYER | # |
|---|---|
| George Rogers (NO) | 378 |
| Earl Campbell (TEN) | 361 |
| Tony Dorsett (DAL) | 342 |
| Walter Payton (CHI) | 339 |
| Ottis Anderson (ARI) | 328 |
| Billy Sims (DET) | 296 |
| William Andrews (ATL) | 289 |
| Wilbert Montgomery (PHI) | 286 |
| Ted Brown (MIN) | 274 |
| Pete Johnson (CIN) | 274 |
| Wendell Tyler (LAR) | 260 |
| Joe Cribbs (BUF) | 257 |
| Chuck Muncie (LAC) | 251 |
| Mike Pruitt (CLE) | 247 |
| Franco Harris (PIT) | 242 |
| Joe Delaney (KC) | 234 |
| Joe Washington (WAS) | 210 |
| Rob Carpenter (TEN) | 208 |
| Tony Collins (NE) | 204 |
| Andra Franklin (MIA) | 201 |
Note: Regular season only.