| PLAYER | # |
|---|---|
| O.J. Simpson (BUF) | 329 |
| Lydell Mitchell (IND) | 289 |
| Chuck Foreman (MIN) | 280 |
| Jim Otis (ARI) | 269 |
| Franco Harris (PIT) | 262 |
| Dave Hampton (ATL) | 250 |
| John Riggins (NYJ) | 238 |
| Mike Thomas (WAS) | 235 |
| Mercury Morris (MIA) | 219 |
| Greg Pruitt (CLE) | 217 |
| Lawrence McCutcheon (LAR) | 213 |
| Robert Newhouse (DAL) | 209 |
| Walter Payton (CHI) | 196 |
| Altie Taylor (DET) | 195 |
| Pete Banaszak (LV) | 187 |
| Jim Braxton (BUF) | 186 |
| Jon Keyworth (DEN) | 182 |
| Ronnie Coleman (TEN) | 175 |
| Tom Sullivan (PHI) | 173 |
| Sam Cunningham (NE) | 169 |
Note: Regular season only.