| PLAYER | # |
|---|---|
| O.J. Simpson (BUF) | 332 |
| Larry Brown (WAS) | 273 |
| Calvin Hill (DAL) | 273 |
| John Brockington (GB) | 265 |
| Dave Hampton (ATL) | 263 |
| Ron Johnson (NYG) | 260 |
| Floyd Little (DEN) | 256 |
| Boobie Clark (CIN) | 254 |
| Lydell Mitchell (IND) | 253 |
| Larry Csonka (MIA) | 219 |
| Tom Sullivan (PHI) | 217 |
| Ed Podolak (KC) | 210 |
| Lawrence McCutcheon (LAR) | 210 |
| Jim Bertelsen (LAR) | 206 |
| Jess Phillips (NO) | 198 |
| Essex Johnson (CIN) | 195 |
| Marv Hubbard (LV) | 193 |
| Franco Harris (PIT) | 188 |
| Emerson Boozer (NYJ) | 182 |
| Chuck Foreman (MIN) | 182 |
Note: Regular season only.