| PLAYER | # |
|---|---|
| Matt Schaub (HOU) | 4,770 |
| Peyton Manning (IND) | 4,500 |
| Tony Romo (DAL) | 4,483 |
| Aaron Rodgers (GB) | 4,434 |
| Tom Brady (NE) | 4,398 |
| Drew Brees (NO) | 4,388 |
| Ben Roethlisberger (PIT) | 4,328 |
| Philip Rivers (LAC) | 4,254 |
| Brett Favre (MIN) | 4,202 |
| Eli Manning (NYG) | 4,021 |
| Kyle Orton (DEN) | 3,802 |
| Kurt Warner (ARI) | 3,753 |
| Jay Cutler (CHI) | 3,666 |
| Jason Campbell (WAS) | 3,618 |
| Joe Flacco (BAL) | 3,613 |
| David Garrard (JAX) | 3,597 |
| Donovan McNabb (PHI) | 3,553 |
| Carson Palmer (CIN) | 3,094 |
| Matt Hasselbeck (SEA) | 3,029 |
| Matt Cassel (KC) | 2,924 |
Note: Regular season only.