| PLAYER | # |
|---|---|
| Drew Brees (NO) | 5,069 |
| Kurt Warner (ARI) | 4,583 |
| Jay Cutler (DEN) | 4,526 |
| Aaron Rodgers (GB) | 4,038 |
| Philip Rivers (LAC) | 4,009 |
| Peyton Manning (IND) | 4,002 |
| Donovan McNabb (PHI) | 3,916 |
| Matt Cassel (NE) | 3,693 |
| Chad Pennington (MIA) | 3,653 |
| David Garrard (JAX) | 3,620 |
| Brett Favre (NYJ) | 3,472 |
| Tony Romo (DAL) | 3,448 |
| Matt Ryan (ATL) | 3,440 |
| Ben Roethlisberger (PIT) | 3,301 |
| Jake Delhomme (CAR) | 3,288 |
| Jason Campbell (WAS) | 3,245 |
| Eli Manning (NYG) | 3,238 |
| Matt Schaub (HOU) | 3,043 |
| Kyle Orton (CHI) | 2,972 |
| Joe Flacco (BAL) | 2,971 |
Note: Regular season only.