| PLAYER | # |
|---|---|
| Drew Brees (NO) | 456 |
| Matt Ryan (ATL) | 415 |
| Ben Roethlisberger (PIT) | 408 |
| Peyton Manning (DEN) | 395 |
| Ryan Tannehill (MIA) | 392 |
| Andrew Luck (IND) | 380 |
| Philip Rivers (LAC) | 379 |
| Eli Manning (NYG) | 379 |
| Tom Brady (NE) | 373 |
| Jay Cutler (CHI) | 370 |
| Matthew Stafford (DET) | 363 |
| Derek Carr (LV) | 348 |
| Joe Flacco (BAL) | 344 |
| Aaron Rodgers (GB) | 341 |
| Andy Dalton (CIN) | 309 |
| Tony Romo (DAL) | 304 |
| Alex Smith (KC) | 303 |
| Colin Kaepernick (SF) | 289 |
| Kyle Orton (BUF) | 287 |
| Russell Wilson (SEA) | 285 |
Note: Regular season only.