| PLAYER | # |
|---|---|
| Matthew Stafford (DET) | 435 |
| Tony Romo (DAL) | 425 |
| Matt Ryan (ATL) | 422 |
| Drew Brees (NO) | 422 |
| Tom Brady (NE) | 401 |
| Peyton Manning (DEN) | 400 |
| Aaron Rodgers (GB) | 371 |
| Matt Schaub (HOU) | 350 |
| Carson Palmer (LV) | 345 |
| Andrew Luck (IND) | 339 |
| Philip Rivers (LAC) | 338 |
| Andy Dalton (CIN) | 329 |
| Sam Bradford (LAR) | 328 |
| Eli Manning (NYG) | 321 |
| Joe Flacco (BAL) | 317 |
| Josh Freeman (TB) | 306 |
| Ryan Fitzpatrick (BUF) | 306 |
| Christian Ponder (MIN) | 300 |
| Brandon Weeden (CLE) | 297 |
| Ben Roethlisberger (PIT) | 284 |
Note: Regular season only.