| PLAYER | # |
|---|---|
| Drew Brees (NO) | 413 |
| Kurt Warner (ARI) | 401 |
| Jay Cutler (DEN) | 384 |
| Peyton Manning (IND) | 371 |
| Donovan McNabb (PHI) | 345 |
| Brett Favre (NYJ) | 343 |
| Aaron Rodgers (GB) | 341 |
| David Garrard (JAX) | 335 |
| Matt Cassel (NE) | 327 |
| Chad Pennington (MIA) | 321 |
| Jason Campbell (WAS) | 315 |
| Philip Rivers (LAC) | 312 |
| Eli Manning (NYG) | 289 |
| Ben Roethlisberger (PIT) | 281 |
| Tony Romo (DAL) | 276 |
| Kyle Orton (CHI) | 272 |
| Matt Ryan (ATL) | 265 |
| Joe Flacco (BAL) | 257 |
| Marc Bulger (LAR) | 251 |
| Matt Schaub (HOU) | 251 |
Note: Regular season only.