| PLAYER | # |
|---|---|
| Drew Brees (NO) | 440 |
| Tom Brady (NE) | 398 |
| Carson Palmer (CIN) | 373 |
| Brett Favre (GB) | 356 |
| Jon Kitna (DET) | 355 |
| Matt Hasselbeck (SEA) | 352 |
| Peyton Manning (IND) | 337 |
| Tony Romo (DAL) | 335 |
| Derek Anderson (CLE) | 298 |
| Eli Manning (NYG) | 297 |
| Jay Cutler (DEN) | 297 |
| Donovan McNabb (PHI) | 291 |
| Kurt Warner (ARI) | 281 |
| Philip Rivers (LAC) | 277 |
| Ben Roethlisberger (PIT) | 264 |
| Jason Campbell (WAS) | 250 |
| Vince Young (TEN) | 238 |
| Marc Bulger (LAR) | 221 |
| Joey Harrington (ATL) | 215 |
| Jeff Garcia (TB) | 209 |
Note: Regular season only.