| PLAYER | # |
|---|---|
| Peyton Manning (IND) | 679 |
| Drew Brees (NO) | 658 |
| Sam Bradford (LAR) | 590 |
| Carson Palmer (CIN) | 586 |
| Matt Schaub (HOU) | 574 |
| Matt Ryan (ATL) | 571 |
| Philip Rivers (LAC) | 541 |
| Eli Manning (NYG) | 539 |
| Mark Sanchez (NYJ) | 507 |
| Kyle Orton (DEN) | 498 |
| Tom Brady (NE) | 492 |
| Chad Henne (MIA) | 490 |
| Joe Flacco (BAL) | 489 |
| Aaron Rodgers (GB) | 475 |
| Josh Freeman (TB) | 474 |
| Donovan McNabb (WAS) | 472 |
| Matt Cassel (KC) | 450 |
| Matt Hasselbeck (SEA) | 444 |
| Ryan Fitzpatrick (BUF) | 441 |
| Jay Cutler (CHI) | 432 |
Note: Regular season only.