1978 NFL Draft Round 1
| YEAR | RND | PICK # | TEAM | PLAYER | POS | COLLEGE |
| 1978 | 1 | 1 | TEN | Earl Campbell | RB | Texas |
| 1978 | 1 | 2 | KAN | Art Still | DE | Kentucky |
| 1978 | 1 | 3 | NOR | Wes Chandler | WR | Florida |
| 1978 | 1 | 4 | NYJ | Chris Ward | T | Ohio St. |
| 1978 | 1 | 5 | BUF | Terry Miller | RB | Oklahoma St. |
| 1978 | 1 | 6 | GNB | James Lofton | WR | Stanford |
| 1978 | 1 | 7 | SFO | Ken MacAfee | TE | Notre Dame |
| 1978 | 1 | 8 | CIN | Ross Browner | DE | Notre Dame |
| 1978 | 1 | 9 | SEA | Keith Simpson | DB | Memphis |
| 1978 | 1 | 10 | NYG | Gordon King | T | Stanford |
| 1978 | 1 | 11 | DET | Luther Bradley | DB | Notre Dame |
| 1978 | 1 | 12 | CLE | Clay Matthews | LB | USC |
| 1978 | 1 | 13 | ATL | Mike Kenn | T | Michigan |
| 1978 | 1 | 14 | LAC | John Jefferson | WR | Arizona St. |
| 1978 | 1 | 15 | ARI | Steve Little | K | Arkansas |
| 1978 | 1 | 16 | CIN | Blair Bush | C | Washington |
| 1978 | 1 | 17 | TAM | Doug Williams | QB | Grambling St. |
| 1978 | 1 | 18 | NWE | Bob Cryder | T | Alabama |
| 1978 | 1 | 19 | ARI | Ken Greene | DB | Washington St. |
| 1978 | 1 | 20 | RAM | Elvis Peacock | RB | Oklahoma |
| 1978 | 1 | 21 | MIN | Randy Holloway | DE | Pittsburgh |
| 1978 | 1 | 22 | PIT | Ron Johnson | DB | East. Michigan |
| 1978 | 1 | 23 | CLE | Ozzie Newsome | TE | Alabama |
| 1978 | 1 | 24 | SFO | Dan Bunz | LB | Long Beach St. |
| 1978 | 1 | 25 | IND | Reese McCall | TE | Auburn |
| 1978 | 1 | 26 | GNB | John Anderson | LB | Michigan |
| 1978 | 1 | 27 | DEN | Don Latimer | NT | Miami (FL) |
| 1978 | 1 | 28 | DAL | Larry Bethea | DT | Michigan St. |
