| PLAYER | # |
|---|---|
| Jonathan Taylor (IND) | 1,139 |
| James Cook (BUF) | 920 |
| Rico Dowdle (CAR) | 788 |
| De'Von Achane (MIA) | 780 |
| J.K. Dobbins (DEN) | 772 |
| Javonte Williams (DAL) | 716 |
| Derrick Henry (BAL) | 704 |
| Jahmyr Gibbs (DET) | 693 |
| Bijan Robinson (ATL) | 679 |
| Breece Hall (NYJ) | 664 |
| Kyren Williams (LAR) | 659 |
| Travis Etienne (JAX) | 656 |
| Christian McCaffrey (SF) | 626 |
| Josh Jacobs (GB) | 608 |
| Saquon Barkley (PHI) | 579 |
| Quinshon Judkins (CLE) | 561 |
| Ashton Jeanty (LV) | 547 |
| D'Andre Swift (CHI) | 544 |
| Kenneth Walker III (SEA) | 539 |
| Tony Pollard (TEN) | 480 |
Note: Regular season only.