| PLAYER | # |
|---|---|
| Priest Holmes (KC) | 1,555 |
| Curtis Martin (NYJ) | 1,513 |
| Stephen Davis (WAS) | 1,432 |
| Ahman Green (GB) | 1,387 |
| Marshall Faulk (LAR) | 1,382 |
| Shaun Alexander (SEA) | 1,318 |
| Corey Dillon (CIN) | 1,315 |
| Ricky Williams (NO) | 1,245 |
| LaDainian Tomlinson (LAC) | 1,236 |
| Garrison Hearst (SF) | 1,206 |
| Anthony Thomas (CHI) | 1,183 |
| Antowain Smith (NE) | 1,157 |
| Dominic Rhodes (IND) | 1,104 |
| Jerome Bettis (PIT) | 1,072 |
| Emmitt Smith (DAL) | 1,021 |
| Lamar Smith (MIA) | 968 |
| Eddie George (TEN) | 939 |
| Stacey Mack (JAX) | 877 |
| Tiki Barber (NYG) | 865 |
| Michael Pittman (ARI) | 846 |
Note: Regular season only.