| PLAYER | # |
|---|---|
| Eric Dickerson (LAR) | 2,105 |
| Walter Payton (CHI) | 1,684 |
| James Wilder (TB) | 1,544 |
| Gerald Riggs (ATL) | 1,486 |
| Wendell Tyler (SF) | 1,262 |
| John Riggins (WAS) | 1,239 |
| Tony Dorsett (DAL) | 1,189 |
| Earnest Jackson (LAC) | 1,179 |
| Ottis Anderson (ARI) | 1,174 |
| Marcus Allen (LV) | 1,168 |
| Sammy Winder (DEN) | 1,153 |
| Greg Bell (BUF) | 1,100 |
| Freeman McNeil (NYJ) | 1,070 |
| George Rogers (NO) | 914 |
| Frank Pollard (PIT) | 851 |
| Rob Carpenter (NYG) | 795 |
| Craig James (NE) | 790 |
| Wilbert Montgomery (PHI) | 789 |
| Larry Moriarty (TEN) | 785 |
| Alfred Anderson (MIN) | 773 |
Note: Regular season only.