| PLAYER | # |
|---|---|
| Jonathan Taylor (IND) | 15 |
| Josh Jacobs (GB) | 11 |
| Jahmyr Gibbs (DET) | 8 |
| Javonte Williams (DAL) | 8 |
| James Cook (BUF) | 7 |
| Jaxson Dart (NYG) | 7 |
| Josh Allen (BUF) | 7 |
| Derrick Henry (BAL) | 6 |
| Zach Charbonnet (SEA) | 6 |
| Tyler Allgeier (ATL) | 6 |
| Cam Skattebo (NYG) | 5 |
| Kyren Williams (LAR) | 5 |
| David Montgomery (DET) | 5 |
| Quinshon Judkins (CLE) | 5 |
| Rico Dowdle (CAR) | 5 |
| Jalen Hurts (PHI) | 5 |
| De'Von Achane (MIA) | 5 |
| Daniel Jones (IND) | 5 |
| Kareem Hunt (KC) | 5 |
| Patrick Mahomes (KC) | 4 |
Note: Regular season only.