| PLAYER | # |
|---|---|
| Maurice Jones-Drew (JAX) | 343 |
| Michael Turner (ATL) | 301 |
| Ray Rice (BAL) | 291 |
| Marshawn Lynch (SEA) | 285 |
| Frank Gore (SF) | 282 |
| Arian Foster (HOU) | 278 |
| Cedric Benson (CIN) | 273 |
| LeSean McCoy (PHI) | 273 |
| Chris Johnson (TEN) | 262 |
| Steven Jackson (LAR) | 260 |
| Michael Bush (LV) | 256 |
| Shonn Greene (NYJ) | 253 |
| Willis McGahee (DEN) | 249 |
| Beanie Wells (ARI) | 245 |
| Rashard Mendenhall (PIT) | 228 |
| Ryan Mathews (LAC) | 222 |
| Reggie Bush (MIA) | 216 |
| Adrian Peterson (MIN) | 208 |
| Matt Forte (CHI) | 203 |
| LeGarrette Blount (TB) | 184 |
Note: Regular season only.