| PLAYER | # |
|---|---|
| Edgerrin James (IND) | 369 |
| Curtis Martin (NYJ) | 367 |
| Emmitt Smith (DAL) | 329 |
| Duce Staley (PHI) | 325 |
| Ricky Watters (SEA) | 325 |
| Eddie George (TEN) | 320 |
| Jerome Bettis (PIT) | 299 |
| Stephen Davis (WAS) | 290 |
| Curtis Enis (CHI) | 287 |
| Dorsey Levens (GB) | 279 |
| Olandis Gary (DEN) | 276 |
| Corey Dillon (CIN) | 263 |
| Terry Allen (NE) | 254 |
| Ricky Williams (NO) | 253 |
| Marshall Faulk (LAR) | 253 |
| James Stewart (JAX) | 249 |
| Tyrone Wheatley (LV) | 242 |
| Mike Alstott (TB) | 242 |
| Charlie Garner (SF) | 241 |
| Errict Rhett (BAL) | 236 |
Note: Regular season only.