| PLAYER | # |
|---|---|
| Matthew Stafford (DET) | 663 |
| Drew Brees (NO) | 657 |
| Tom Brady (NE) | 611 |
| Eli Manning (NYG) | 589 |
| Philip Rivers (LAC) | 582 |
| Ryan Fitzpatrick (BUF) | 569 |
| Matt Ryan (ATL) | 566 |
| Josh Freeman (TB) | 551 |
| Mark Sanchez (NYJ) | 543 |
| Joe Flacco (BAL) | 542 |
| Tony Romo (DAL) | 522 |
| Matt Hasselbeck (TEN) | 518 |
| Cam Newton (CAR) | 517 |
| Andy Dalton (CIN) | 516 |
| Ben Roethlisberger (PIT) | 513 |
| Aaron Rodgers (GB) | 502 |
| Colt McCoy (CLE) | 463 |
| Rex Grossman (WAS) | 458 |
| Tarvaris Jackson (SEA) | 450 |
| Alex Smith (SF) | 445 |
Note: Regular season only.