2006 NFL Draft Round 5
| YEAR | RND | PICK # | TEAM | PLAYER | POS | COLLEGE |
| 2006 | 5 | 134 | BUF | Kyle Williams | DT | LSU |
| 2006 | 5 | 135 | NOR | Rob Ninkovich | DE | Purdue |
| 2006 | 5 | 136 | NWE | Ryan O'Callaghan | T | California |
| 2006 | 5 | 137 | TEN | Terna Nande | LB | Miami (OH) |
| 2006 | 5 | 138 | DAL | Pat Watkins | DB | Florida St. |
| 2006 | 5 | 139 | ATL | Quinn Ojinnaka | G | Syracuse |
| 2006 | 5 | 140 | SFO | Parys Haralson | DE | Tennessee |
| 2006 | 5 | 141 | DET | Jonathan Scott | T | Texas |
| 2006 | 5 | 142 | ARI | Brandon Johnson | LB | Louisville |
| 2006 | 5 | 143 | BUF | Brad Butler | T | Virginia |
| 2006 | 5 | 144 | RAM | Marques Hagans | WR | Virginia |
| 2006 | 5 | 145 | CLE | Jerome Harrison | RB | Washington St. |
| 2006 | 5 | 146 | BAL | Dawan Landry | DB | Georgia Tech |
| 2006 | 5 | 147 | PHI | Jeremy Bloom | DB | Colorado |
| 2006 | 5 | 148 | GNB | Ingle Martin | QB | Furman |
| 2006 | 5 | 149 | MIN | Greg Blue | DB | Georgia |
| 2006 | 5 | 150 | NYJ | Jason Pociask | TE | Wisconsin |
| 2006 | 5 | 151 | LAC | Tim Dobbins | LB | Iowa St. |
| 2006 | 5 | 152 | CLE | DeMario Minter | DB | Georgia |
| 2006 | 5 | 153 | WAS | Anthony Montgomery | NT | Minnesota |
| 2006 | 5 | 154 | KAN | Marcus Maxey | DB | Miami (FL) |
| 2006 | 5 | 155 | CAR | Jeff King | TE | Virginia Tech |
| 2006 | 5 | 156 | TAM | Julian Jenkins | DE | Stanford |
| 2006 | 5 | 157 | CIN | A.J. Nicholson | LB | Florida St. |
| 2006 | 5 | 158 | NYG | Charlie Peprah | DB | Alabama |
| 2006 | 5 | 159 | CHI | Mark Anderson | DE | Alabama |
| 2006 | 5 | 160 | JAX | Brent Hawkins | DE | Illinois St. |
| 2006 | 5 | 161 | DEN | Chris Kuper | G | North Dakota |
| 2006 | 5 | 162 | IND | Michael Toudouze | G | TCU |
| 2006 | 5 | 163 | SEA | David Kirtman | RB | USC |
| 2006 | 5 | 164 | PIT | Omar Jacobs | QB | Bowling Green |
| 2006 | 5 | 165 | GNB | Tony Moll | T | Nevada |
| 2006 | 5 | 166 | BAL | Quinn Sypniewski | TE | Colorado |
| 2006 | 5 | 167 | PIT | Charles Davis | TE | Purdue |
| 2006 | 5 | 168 | PHI | Omar Gaither | LB | Tennessee |
| 2006 | 5 | 169 | TEN | Jesse Mahelona | DT | Tennessee |
