2022 NFL Draft Round 4
| YEAR | RND | PICK # | TEAM | PLAYER | POS | COLLEGE |
| 2022 | 4 | 106 | TAM | Cade Otton | TE | Washington |
| 2022 | 4 | 107 | HOU | Dameon Pierce | RB | Florida |
| 2022 | 4 | 108 | CLE | Perrion Winfrey | DT | Oklahoma |
| 2022 | 4 | 109 | SEA | Coby Bryant | CB | Cincinnati |
| 2022 | 4 | 110 | BAL | Daniel Faalele | T | Minnesota |
| 2022 | 4 | 111 | NYJ | Max Mitchell | T | Louisiana |
| 2022 | 4 | 112 | NYG | Daniel Bellinger | TE | San Diego St. |
| 2022 | 4 | 113 | WAS | Percy Butler | SAF | Louisiana |
| 2022 | 4 | 114 | NYG | Dane Belton | DB | Iowa |
| 2022 | 4 | 115 | DEN | Damarri Mathis | DB | Pittsburgh |
| 2022 | 4 | 116 | DEN | Eyioma Uwazurike | DE | Iowa St. |
| 2022 | 4 | 117 | NYJ | Micheal Clemons | DT | Texas A&M |
| 2022 | 4 | 118 | MIN | Akayleb Evans | DB | Missouri |
| 2022 | 4 | 119 | BAL | Jalyn Armour-Davis | DB | Alabama |
| 2022 | 4 | 120 | CAR | Brandon Smith | LB | Penn St. |
| 2022 | 4 | 121 | NWE | Jack Jones | DB | Arizona St. |
| 2022 | 4 | 122 | LVR | Zamir White | RB | Georgia |
| 2022 | 4 | 123 | LAC | Isaiah Spiller | RB | Texas A&M |
| 2022 | 4 | 124 | CLE | Cade York | K | LSU |
| 2022 | 4 | 125 | MIA | Erik Ezukanma | WR | Texas Tech |
| 2022 | 4 | 126 | LVR | Neil Farrell | DT | LSU |
| 2022 | 4 | 127 | NWE | Pierre Strong | RB | South Dakota St. |
| 2022 | 4 | 128 | BAL | Charlie Kolar | TE | Iowa St. |
| 2022 | 4 | 129 | DAL | Jake Ferguson | TE | Wisconsin |
| 2022 | 4 | 130 | BAL | Jordan Stout | P | Penn St. |
| 2022 | 4 | 131 | TEN | Hassan Haskins | RB | Michigan |
| 2022 | 4 | 132 | GNB | Romeo Doubs | WR | Nevada |
| 2022 | 4 | 133 | TAM | Jake Camarda | P | Georgia |
| 2022 | 4 | 134 | SFO | Spencer Burford | OL | Texas-San Antonio |
| 2022 | 4 | 135 | KAN | Joshua Williams | CB | Fayetteville St. |
| 2022 | 4 | 136 | CIN | Cordell Volson | T | North Dakota St. |
| 2022 | 4 | 137 | NWE | Bailey Zappe | QB | Western Kentucky |
| 2022 | 4 | 138 | PIT | Calvin Austin | WR | Memphis |
| 2022 | 4 | 139 | BAL | Isaiah Likely | TE | Coastal Carolina |
| 2022 | 4 | 140 | GNB | Zach Tom | OL | Wake Forest |
| 2022 | 4 | 141 | BAL | Damarion Williams | CB | Houston |
| 2022 | 4 | 142 | LAR | Decobie Durant | DB | South Carolina St. |
| 2022 | 4 | 143 | TEN | Chigoziem Okonkwo | TE | Maryland |
