2000 NFL Draft Round 1
| YEAR | RND | PICK # | TEAM | PLAYER | POS | COLLEGE |
| 2000 | 1 | 1 | CLE | Courtney Brown | DE | Penn St. |
| 2000 | 1 | 2 | WAS | LaVar Arrington | LB | Penn St. |
| 2000 | 1 | 3 | WAS | Chris Samuels | T | Alabama |
| 2000 | 1 | 4 | CIN | Peter Warrick | WR | Florida St. |
| 2000 | 1 | 5 | BAL | Jamal Lewis | RB | Tennessee |
| 2000 | 1 | 6 | PHI | Corey Simon | DT | Florida St. |
| 2000 | 1 | 7 | ARI | Thomas Jones | RB | Virginia |
| 2000 | 1 | 8 | PIT | Plaxico Burress | WR | Michigan St. |
| 2000 | 1 | 9 | CHI | Brian Urlacher | LB | New Mexico |
| 2000 | 1 | 10 | BAL | Travis Taylor | WR | Florida |
| 2000 | 1 | 11 | NYG | Ron Dayne | RB | Wisconsin |
| 2000 | 1 | 12 | NYJ | Shaun Ellis | DE | Tennessee |
| 2000 | 1 | 13 | NYJ | John Abraham | DE | South Carolina |
| 2000 | 1 | 14 | GNB | Bubba Franks | TE | Miami (FL) |
| 2000 | 1 | 15 | DEN | Deltha O'Neal | DB | California |
| 2000 | 1 | 16 | SFO | Julian Peterson | LB | Michigan St. |
| 2000 | 1 | 17 | LAS | Sebastian Janikowski | K | Florida St. |
| 2000 | 1 | 18 | NYJ | Chad Pennington | QB | Marshall |
| 2000 | 1 | 19 | SEA | Shaun Alexander | RB | Alabama |
| 2000 | 1 | 20 | DET | Stockar McDougle | T | Oklahoma |
| 2000 | 1 | 21 | KAN | Sylvester Morris | WR | Jackson St. |
| 2000 | 1 | 22 | SEA | Chris McIntosh | T | Wisconsin |
| 2000 | 1 | 23 | CAR | Rashard Anderson | DB | Jackson St. |
| 2000 | 1 | 24 | SFO | Ahmed Plummer | DB | Ohio St. |
| 2000 | 1 | 25 | MIN | Chris Hovan | DT | Boston Col. |
| 2000 | 1 | 26 | BUF | Erik Flowers | DE | Arizona St. |
| 2000 | 1 | 27 | NYJ | Anthony Becht | TE | West Virginia |
| 2000 | 1 | 28 | IND | Rob Morris | LB | BYU |
| 2000 | 1 | 29 | JAX | R. Jay Soward | WR | USC |
| 2000 | 1 | 30 | TEN | Keith Bulluck | LB | Syracuse |
| 2000 | 1 | 31 | RAM | Trung Canidate | RB | Arizona |
