1999 NFL Draft Round 1
| YEAR | RND | PICK # | TEAM | PLAYER | POS | COLLEGE |
| 1999 | 1 | 1 | CLE | Tim Couch | QB | Kentucky |
| 1999 | 1 | 2 | PHI | Donovan McNabb | QB | Syracuse |
| 1999 | 1 | 3 | CIN | Akili Smith | QB | Oregon |
| 1999 | 1 | 4 | IND | Edgerrin James | RB | Miami (FL) |
| 1999 | 1 | 5 | NOR | Ricky Williams | RB | Texas |
| 1999 | 1 | 6 | RAM | Torry Holt | WR | North Carolina St. |
| 1999 | 1 | 7 | WAS | Champ Bailey | DB | Georgia |
| 1999 | 1 | 8 | ARI | David Boston | WR | Ohio St. |
| 1999 | 1 | 9 | DET | Chris Claiborne | LB | USC |
| 1999 | 1 | 10 | BAL | Chris McAlister | DB | Arizona |
| 1999 | 1 | 11 | MIN | Daunte Culpepper | QB | Central Florida |
| 1999 | 1 | 12 | CHI | Cade McNown | QB | UCLA |
| 1999 | 1 | 13 | PIT | Troy Edwards | WR | Louisiana Tech |
| 1999 | 1 | 14 | KAN | John Tait | T | BYU |
| 1999 | 1 | 15 | TAM | Anthony McFarland | DT | LSU |
| 1999 | 1 | 16 | TEN | Jevon Kearse | DE | Florida |
| 1999 | 1 | 17 | NWE | Damien Woody | C | Boston Col. |
| 1999 | 1 | 18 | LAS | Matt Stinchcomb | G | Georgia |
| 1999 | 1 | 19 | NYG | Luke Petitgout | T | Notre Dame |
| 1999 | 1 | 20 | DAL | Ebenezer Ekuban | DE | North Carolina |
| 1999 | 1 | 21 | ARI | L.J. Shelton | T | East. Michigan |
| 1999 | 1 | 22 | SEA | Lamar King | DE | Saginaw Valley St. |
| 1999 | 1 | 23 | BUF | Antoine Winfield | DB | Ohio St. |
| 1999 | 1 | 24 | SFO | Reggie McGrew | DT | Florida |
| 1999 | 1 | 25 | GNB | Antuan Edwards | DB | Clemson |
| 1999 | 1 | 26 | JAX | Fernando Bryant | DB | Alabama |
| 1999 | 1 | 27 | DET | Aaron Gibson | T | Wisconsin |
| 1999 | 1 | 28 | NWE | Andy Katzenmoyer | LB | Ohio St. |
| 1999 | 1 | 29 | MIN | Dimitrius Underwood | DT | Michigan St. |
| 1999 | 1 | 30 | ATL | Patrick Kerney | DE | Virginia |
| 1999 | 1 | 31 | DEN | Al Wilson | LB | Tennessee |
