The early NFL week two point spreads and lines are available.
Here are biggest betting favorites for the next week: Cleveland Browns-Baltimore Ravens (BAL by 11.5), Buffalo Bills-New York Jets (BUF by 6.5), Carolina Panthers-Arizona Cardinals (ARI by 6.5) and the New York Giants-Dallas Cowboys (DAL by 5.5).
Getting into the lines, home teams are the favorites by a margin of 10-6.
Here are the latest point spread odds for week 2:
| 9/11 8:15 | Washington Commanders (1-0) at Green Bay Packers (1-0) | GB -3.5 |
| 9/14 1:00 | Jacksonville Jaguars (1-0) at Cincinnati Bengals (1-0) | CIN -3.5 |
| 9/14 1:00 | New York Giants (0-1) at Dallas Cowboys (0-1) | DAL -5.5 |
| 9/14 1:00 | Chicago Bears (0-1) at Detroit Lions (0-1) | DET -5.5 |
| 9/14 1:00 | Los Angeles Rams (1-0) at Tennessee Titans (0-1) | LAR -5.5 |
| 9/14 1:00 | New England Patriots (0-1) at Miami Dolphins (0-1) | MIA -1.5 |
| 9/14 1:00 | San Francisco 49ers (1-0) at New Orleans Saints (0-1) | SF -4.5 |
| 9/14 1:00 | Buffalo Bills (1-0) at New York Jets (0-1) | BUF -6.5 |
| 9/14 1:00 | Seattle Seahawks (0-1) at Pittsburgh Steelers (1-0) | PIT -2.5 |
| 9/14 1:00 | Cleveland Browns (0-1) at Baltimore Ravens (0-1) | BAL -11.5 |
| 9/14 4:05 | Denver Broncos (1-0) at Indianapolis Colts (1-0) | DEN -1.5 |
| 9/14 4:05 | Carolina Panthers (0-1) at Arizona Cardinals (1-0) | ARI -6.5 |
| 9/14 4:25 | Philadelphia Eagles (1-0) at Kansas City Chiefs (0-1) | PHI -1.5 |
| 9/14 8:20 | Atlanta Falcons (0-1) at Minnesota Vikings (1-0) | MIN -3.5 |
| 9/15 7:00 | Tampa Bay Buccaneers (1-0) at Houston Texans (0-1) | HOU -2.5 |
| 9/15 10:00 | Los Angeles Chargers (1-0) at Las Vegas Raiders (1-0) | LAC -3.5 |